Table 6 Titration Schedule for Basal and Prandial Insulin [6]
Blood Glucose Levels for 3 Consecutive Days (Fasting, Preprandial, or Bedtime) | Adjust Basal Insulin Dose (U)* | Adjust Rapid-Acting Insulin Dose (U per Injection) |
|---|---|---|
≥180 mg/dL | +8 | +3 |
160–180 mg/dL | +6 | +2 |
140–160 mg/dL | +4 | +2 |
120–140 mg/dL | +2 | +1 |
100–120 mg/dL | +1 | Maintain dose |
80–100 mg/dL | Maintain dose | - 1 |
60–80 mg/dL†| - 2 | - 2 |
< 60 mg/dL†| - 4 | - 4 |
Comments: | • For elevated fasting blood glucose levels, adjust only the basal insulin dose | • For elevated preprandial blood glucose at lunchtime, adjust breakfast rapid-acting insulin dose • For elevated preprandial blood glucose at dinnertime, adjust lunchtime rapid-acting insulin dose • For elevated bedtime blood glucose, adjust dinnertime rapid-acting insulin dose |